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Fly.exe

Runs the complete released Drosophila male CNS connectome (165,122 neurons, 25.5M edges) inside a physical fly body, in closed loop, on one GPU.

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GITHUB · launched Sep 12, 2026 · 16 upvotes (top 48%) · 0 views

Niche: computational biology and chemistry software · 119 launches, 7 in the last 7 days ▲ +17% · Explore this niche →

Category and tags

  • Horizontal
  • Hardware & robotics
  • Developer
  • Not AI
  • Hobby / open-source project
  • computational-neuroscience
  • connectome
  • drosophila
  • gpu
  • mujoco
  • simulation
  • +1 more

Visit website ↗ Source listing ↗

Could you build this?

No Simulating the entire Drosophila connectome (165k+ spiking neurons and 25M synapses) in closed loop with physical body dynamics on a single GPU is cutting-edge computational neuroscience and GPU systems research.

What it would actually take: This architecture requires high-performance CUDA/C++ kernels implementing large-scale sparse matrix spiking neural network (SNN) dynamics coupled with a real-time biomechanical physics engine (such as MuJoCo or custom GPU physics). The hard part is achieving closed-loop sensorimotor latency (<10ms) while computing continuous neural integration across 25.5 million graph edges on single-GPU memory architectures. It demands PhD-level computational neuroscience, graph computing, and high-performance GPU optimization expertise.

Competitors

Other products that read as similar to this one : 127 launches clear the similarity bar, closest 8 shown.

Attention rank: #72 of 128 (itself plus its competitors, highest first, normalized so YC and Product Hunt are compared fairly).

Launched 301 days after the earliest competitor.

  • fly-self-driving · github · 2026-09-13 · 22 upvotes · similarity 0.72
  • FLYBOX · ph · 2026-09-25 · 57 upvotes · similarity 0.69
  • awesome-fly · github · 2026-09-12 · 382 upvotes · similarity 0.67
  • FlyBrain-HalfLife · github · 2026-09-12 · 24 upvotes · similarity 0.67
  • A Flys Life · ph · 2026-09-26 · 2 upvotes · similarity 0.63
  • flycoinrh · github · 2026-09-10 · 174 upvotes · similarity 0.63
  • amfly · github · 2026-09-14 · 26 upvotes · similarity 0.61
  • Human vs Brain · ph · 2026-09-18 · 2 upvotes · similarity 0.61

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